By Marlene A. Jacobson (auth.), Luiz Belardinelli, Amir Pelleg (eds.)
This ebook incorporates a number of lectures given throughout the fifth foreign Symposium on Adenosine and Adenine Nucleotides, lately held in Philadelphia, Pennsylvania.
Adenosine and Adenine Nucleotides: From Molecular Biology toIntegrative Physiology covers quite a lot of matters from molecular and mobile biology to medical purposes. an excellent emphasis has been put on leading edge info derived from reports utilizing molecular and mobile biology suggestions utilized to the sphere of adenosine and adenine nucleotide examine. The ebook additionally contains details on very likely promising advancements within the healing purposes of adenosine similar medications and ATP. The culture of previous conferences can also be maintained through together with within the application shows of latest examine within the parts of purine metabolism and body structure, and pharmacology of adenosine and adenine nucleotides.
Adenosine and Adenine Nucleotides: From Molecular Biology toIntegrative Physiology is a wonderful, up to date reference publication for uncomplicated and scientific scientists within the box of adenosine and adenine nucleotides.
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Extra resources for Adenosine and Adenine Nucleotides: From Molecular Biology to Integrative Physiology
Example text
The existence of a prejunctional adenosine receptor, termed A 3 , was originally proposed on the basis of antagonist effects in the frog neuromuscular junction by Riberio and Sebastiao [20}, since the rank-order activity of antagonists in this preparation did not correlate with either Al or Az receptor pharmacology. At the Purines '92 meeting in Milan (I5}, the evidence for the existence of this receptor was discussed and, TABLE 5-1. Adenosine purinoceptors Adenosine receptor Human clone aaa (SwissProt Number) Al 326 aa (545235) Aza 412 aa (P29274) A 2b A3 328 aa (P29275) 318 aa (L22607) A4 Not yet cloned Agonists Antagonists CHA,CPA,CCPA,NECA, NNC 21-0041 CGS 21680, MPEA CPX, CPT, KFM 19, MDL 102,234, CGS 15943 KF 17837, CSC, CGS 15943, CP 66713, AMBP Xanthines b I-ABPOX NECA N 6 -benzyl NECA, N 6 _ iodobenzyl MECA CV 1808 CGS 15943N • Amino acids.
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