By Richard A. Houghten, Michal Lebl
content material: man made methodologies, good part synthesis, good section natural synthesis, combinatorial options --
Analytical and biophysical tools, peptides and proteins folding, de novo layout of peptides and proteins --
Biologically lively peptides, enzyme inhibitors, peptide neurotoxins and antibiotics, peptidomimetics, peptide and peptidomimetic therapeutics and supply --
Peptide conjugates, glycopeptides and lipopeptides, transmembrane peptides and proteins, receptors and receptor interactions, sign transduction --
Peptides in immunology, artificial vaccines, molecular mechanisms of illnesses, peptides in diagnostics, pharmacology and biotechnology, peptide supply approaches.
Read or Download Peptides : the wave of the future : proceedings of the Second International and the Seventeenth American Peptide Symposium PDF
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Extra info for Peptides : the wave of the future : proceedings of the Second International and the Seventeenth American Peptide Symposium
Example text
For use in tre"t· ment of peptic ulcer disease, skin infect ions, periodonta l dise;lse, sySIC'mic nosocomial infC'C tions. and bovine mastiri~; St'C' Chaptl'r 15. Aggenix, Inc .. sequesrering glycoprmein as Human lactoferr in a n antibaClC'rial drug. biphenyl vancomyci n deri ... ative that has considernbh' LY333328 higher pCHenCY than vancomycin; it is currently undergoing tesl· ing by Eli Lilly a~ a ... e; see Chapter 12. A 4'·substituted anthracycline. ; cardiotoxic than doxorubkin while retaining the efficacy; set' Chapter 20.
Why Do W~ ANTI~INFECTIVES Nftd Nnr Antibiotics? s. surgeon general confidently predicted that the war against infectious diseases finally had been won, not on ly in the United States, b UI worldwide. T hat attitude was borne out by government policies in the 1980s. in which funding for infect iouS disease research was not a high priority (17). Ouring the same period, most of the major pharmaceutical companies dec reased research and development on anti-infectives, at least part ly because of the absence of economic incentive ( 16).
II . IMPORTANCE OF CONTINUED DEVELOPMENT OF A. Why Do W~ ANTI~INFECTIVES Nftd Nnr Antibiotics? s. surgeon general confidently predicted that the war against infectious diseases finally had been won, not on ly in the United States, b UI worldwide. T hat attitude was borne out by government policies in the 1980s. in which funding for infect iouS disease research was not a high priority (17). Ouring the same period, most of the major pharmaceutical companies dec reased research and development on anti-infectives, at least part ly because of the absence of economic incentive ( 16).