Biotechnology and Genetic Engineering Reviews, Vol. 25 by Stephen E. Harding

By Stephen E. Harding

Containing more than a dozen original, significant overview articles from authors released in top journals and covering vital advancements in commercial, agricultural, and clinical purposes of biotechnology, this most recent version from the well-established hardcover assessment sequence focuses totally on the genetic manipulation of organisms. protecting matters starting from gene expression and genetic rules to plant bioreactors and enzymatic processing, this reference will profit scholars within the fields of biochemistry, genetics, molecular biology, and pharmaceutical sciences.

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2007). All these methods have been developed for S-system models. A procedure that is specific for GMA models and use branch and bound methods has been proposed. , 2006). , 2006). This strategy emphasizes the utility of using smoothing techniques for representing the time course of some variables while fitting parameter values. , 2007). Mathematical formalisms based on approximated kinetic representations 29 What must be emphasized is that parameter identification from dynamic data is a difficult task that must overcome the following problems: (1) Collection of appropriate data sets.

Signal propagation and accuracy of representation. J Biol Chem. 271: 7927-7941. C. A. (1996b). Model assessment and refinement using strategies from biochemical systems theory: application to metabolism in human red blood cells. J Theor Biol. 179: 329-368. , Tegner, J. and Ravasi, T. (2006). Transcriptional network dynamics in macrophage 36 R. Alves et al. activation. Genomics. 88: 133-142. J. and Teusink, B. (2006). Accelerating the reconstruction of genome-scale metabolic networks. BMC Bioinformatics.

130: 329-345. R. and Collado-Vides, J. (2003). Regulatory network of Escherichia coli: Consistency between literature knowledge and microarray profiles. Genome Research. 13: 2435-2443. L. H. (2007). Synthetic gene circuits: design with directed evolution. Annu Rev Biophys Biomol Struct. 36: 1-19. Hatzimanikatis, V. (1999). Nonlinear metabolic control analysis. Metab Eng. 1: 75-87. Hatzimanikatis, V. E. (1996). MCA has more to say. J Theor Biol. 182: 233-242. A. J. (2004). Metabolic networks: enzyme function and metabolite structure.

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