Sex and Gender Aspects in Clinical Medicine by Vera Regitz-Zagrosek (auth.), Sabine Oertelt-Prigione, Vera

By Vera Regitz-Zagrosek (auth.), Sabine Oertelt-Prigione, Vera Regitz-Zagrosek (eds.)

This booklet is a concise, effortless to learn expert textual content with a spotlight on sensible features. All chapters comprise tables on sex/gender adjustments in signs and administration and a sequence of feedback to the beginner within the box. Chapters are specialty-specific. the point of interest isn't really on women’s future health, however the presentation of adjustments in medical indicators, administration and results in men and women. Gender drugs strives to hire the data approximately those alterations to enhance analysis, greater comprehend pathogenesis and boost patient-oriented therapy.

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Recently, it was shown that about 10% of patients die early from cardiac rupture and that these are predominantly men. 24,25 Generally, female mice display lower mortality after MI and more efficient myocardial remodeling with less left ventricular cavity dilation than males (Fig. 26 Ion channel expression has also been implied in the beneficial effect of postMI exercise on the limitation of infarct size, which appears increasingly beneficial in female rats over time. Blood of male patients displays an increased viscosity, more red blood cell aggregation and deformability compared to women, and enhanced primary haemostatic activity,27 with increased rates of aspirin resistance.

Most important clinical consequences of hypertension are related to end-organ damage in the vasculature, kidney, heart, leading to heart failure, stroke, and renal disease. e. 179 Daytime SBP might be the best predictor of LV mass in women. 2 Sex and gender differences in clinical manifestation in cardiology Disease Myocardial infarction Coronary artery disease Hypertension Heart failure Cardiomyopathies Women • Greater diversity of symptoms, vagal activation. nausea, arm/back/jaw ache, general weakness and sweating, craniofacial pain in the absence of chest pain.

The symptoms are less well recognized in female patients, by the patients and their doctors, leading to longer delays in help-seeking behavior, in longer prehospital times, in longer doorto-needle times. Some factors for delay are age, type of MI, absence of knowledge about thrombolytics, or not wanting to trouble others; others were perception of MI as a “male” problem,16 tendency to self-medicate16 associated with lack of recognition of symptoms. Sex Man Women 20 10 0 ≤40 41–50 51–60 61–70 Age in years 71–80 81–90 Fig.

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