By Andrea Spanu
This thesis stories on a unique procedure for extracellular recordings of the job of excitable cells, which is determined by an natural, charge-modulated field-effect transistor (FET) referred to as OCMFET. The e-book exhibits how, due to the intrinsic biocompatibility, lightness, and inexpensiveness of the fabric used, this new method is ready to conquer a number of difficulties general of of “classic” digital and bioelectronic. It offers a whole description of the approach, including a complete document of the winning experimental trials performed on either cardiac and nerve cells, and a concise but finished review of bioelectronic interfaces and natural sensors for electrophysiological applications.
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Example text
It has been demonstrated that the previous stimulation mechanism cause no harm to the cell, though it may induce temporary electroporation of the cell membrane [40]. 25) gJ dt i i where gJM and V0i are the membrane conductance and the reverse potential of the ith ion respectively. The bidirectional circuit to which the Eqs. 25 refer to, is shown in Fig. 11b. During the following years, several hybrid circuits have been studied, such as chip/neuron/neuron/chip [40] and neuron/chip/neuron circuits [50].
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