By Jacqueline Hayles, Paul Nurse (auth.), J. C. Ormrod, D. Francis (eds.)
Considerable advances were made in our realizing of the eukaryotic telephone cycle on the molecular point over the last 20 years or so, quite in yeast and in animal structures. notwithstanding, in simple terms some time past 3 or 4 years has growth been made in crops on the molecular point. the current quantity brings jointly molecular biologists, phone biologists and physiologists to debate this contemporary growth and the way it pertains to our figuring out of the law of plant development and development.
the outlet paper summarises the development which has been made with fission yeast. next papers discover what's recognized approximately cellphone cycle keep watch over on the molecular point in vegetation, and approximately mobile cycle law in particular physiological structures, finishing with precis papers on cellphone department in roots and shoots.
The publication includes up to date findings on a basic point of plant progress and improvement, and as such can be of specific curiosity to complex undergraduates, postgraduates and study scientists within the fields of molecular biology, phone biology and physiology.
Read or Download Molecular and Cell Biology of the Plant Cell Cycle: Proceedings of a meeting held at Lancaster University, 9–10th April, 1992 PDF
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Additional resources for Molecular and Cell Biology of the Plant Cell Cycle: Proceedings of a meeting held at Lancaster University, 9–10th April, 1992
Example text
The S. pombe cdc2 gene has been identified as being required for passage through both the Gl and G2 control points [38]. This gene is conserved in other organisms, and is homologous to a S. cerevisiae gene, namely CDC28 [31]. g. 47, 15,42]. Dephosphorylation of cdc2 is required for its G2 activity, but once cells have passed through G2, cdc2 becomes phosphorylated again prior to entry into G 1. Control of the levels of phosphorylated cdc2 in G2 occurs via cdc25 [44], which has recently been shown to be a protein phosphatase [11].
20. Finkelstein R, Estelle M, Martinez-Zapater J and Sommerville C (1988) Arabidopsis as a tool for the identification of genes involved in plant development. In: Temporal and Spatial Regulation of Plant Genes. Verma DPS and Goldberg RB (eds) pp. 1-25. Springer, New York. 32 21. Gautier J, Solomon MJ, Booher RN, Fernando Bazan J and Kirschner MW (1991) cdc25 is a specific tyrosine phosphatase that directly activates p34 cdc2 . Cell 67: 197-211. 22. Gorst J, Sek FJ and John PCL (1991) Levels of p34cdc2 _like protein in dividing, differentiating and dedifferentiating cells of carrot.
Four S. pombe genes which have been identified as being regulated during the cell cycle are: cdc22 - which encodes the regulatory subunit 37 of ribonucleotide reductase [14], the genes which encode the histones, H2A and H2B [39] and cdc25 [34]. g. cdc22 at G liS, the histones genes (H2A and H2B) in Sand cdc25 at late S/G2. Deletion analysis and use of reporter gene fusions have been used to identify promoter elements responsible for this cell cycle control. In particular MluI elements promote expression at G liS in S.