Isoquinoline Alkaloids Research 1972–1977 by Maurice Shamma

By Maurice Shamma

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For a thorough discussion of the synthesis of 4-oxy- and 4-ketotetrahydroisoquinolines, see J. M. Bobbitt, Adv. Heterocycl. , 15, 99 (1973). 20. S. Teitel, J. O'Brien, and A. Brossi, J. Med. , 15, 845 (1972). For a compilation of the NMR spectra of monophenolic tetrahydroisoquinoline salts, see F. Schenker, R. A. Schmidt, T. Williams, and A. Brossi, J. Heterocycl. , 8, 665 (1971). 21. S. Teitel, J. O'Brien, W. Pool, and A. Brossi, J. Med. , 17, 134 (1974). 22. A. Brossi, A. Focella, and S. Teitel, Helv.

60. W. E. McEwen and R. L. Cobb, Chem. , 55, 511 (1955). 61. F. D. Popp, Adv. Heterocycl. , 9, 1 (1968). 62. F. D. Popp, Heterocycles, 1, 165 (1973). 63. J. Knabe and A. Frie, Arch. , 306, 648 (1973). For a versatile new synthesis of Reissert compounds using an acid chloride and trimethylsilyl cyanide in methylene chloride, see S. Ruchirawat, N. Phadungkul, M. Chuankamnerdkarn, and C. Thebtaranonth, Heterocycles, 6, 43 (1977). 64. H. W. Gibson, F. D. Popp, and A. Catala, J. Heterocycl. , 1, 251 (1964).

Knabe, Arch. , 292, 416 (1959). 49. D. E. Schwartz and J. Rieder, Clin. Chim. Acta, 6, 453 (1971). 50. J. Arthur, F. de Silva, N. Strojny, and N. Munno, J. Pharm. , 62, 1066 (1973). 51. K. C. Agrawal, R. J. Cushley, S. R. Lipsky, J. R. Wheaton, and A. C. Sartorelli, J. Med. , 15, 192 (1972); and K. C. Agrawal, P. D. Mooney, and A. C. Sartorelli, J. Med. , 19, 970 (1976). 52. Y. Ogata and Y. Sawaki, J. Am. Chem. , 95, 4692 (1973). 53. H. Stamm and J. Hoenicke, Arch. , 307, 340 (1974). 54. O. Hoshino, K.

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