Idealistische morphologue und phylogenetik by Naef A

By Naef A

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References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 19 19 21 21 24 24 24 24 25 26 26 27 27 28 Introduction: The Glycoprotein Folding Quality Control Almost one-third of proteins synthesized by eukaryotic cells belong to the secretory pathway, entering the endoplasmic reticulum (ER) either co- or posttranslationally. In the ER, proteins acquire their native tertiary fold, disulfide bonds are formed, and in some cases, they assemble into oligomeric structures.

References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 4 5 5 6 7 7 7 9 9 10 10 10 10 10 11 Introduction Glycosphingolipids (GSLs) occur in most of all cell membranes of vertebrates and lower animals, as well as in plants. They are major component in lipid microdomains or lipid rafts to play important roles in a wide range of physiological and pathophysiological processes. Glucosylceramide (GlcCer) is a key precursor lipid for the synthesis of over 400 GSLs with different sugar chain structures (Fig.

Future Perspectives . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Cross-References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . GalCer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Ganglio Series .

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