By Davor Jezek
Atlas at the Human Testis: basic Morphology and Pathology provides histological illustrative fabric from paraffin and semi-thin sections of the human testis that are typically utilized in the evaluate of testicular morphology, permitting an early detection of carcinoma in situ and extra complex pathological adjustments of the testicular parenchyma. The early detection of melanoma in situ is predicated at the cautious morphological research of the biopsy and immunohistochemistry (IHC). as a result, this atlas comprises targeted descriptions of IHC equipment in addition to smooth molecular organic tools akin to DNA microarrays and proteomics and complicated microscopy thoughts regarding the testicular biopsy.
Adequate assessment of the testicular biopsy ends up in excessive medication charges of testicular neoplasms which are used as a foundation to effectively deal with infertility in men.
Atlas at the Human Testis: general Morphology and Pathology is a precious reference device with a purpose to attract andrologists, urologists, pathologists, scientific embryologists, in addition to reproductive biology scientists.
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Extra info for Atlas on the Human Testis: Normal Morphology and Pathology
Example text
17 A tissue block is placed in the holder and manually trimmed with a blade using an eyepiece magnifier. ASH arc segment holder, KS micrometeradjustable knife stage, MK macro-knob, mK micro-knob, UA ultramicrotome arm Fig. 18 A tissue block is placed in the holder so that two-thirds of the block is inside the holder and one-third protrudes from it. When the block is trimmed, a tissue block holder (TBH) is placed in the arc segment holder (ASH) and positioned on the ultramicrotome arm. ASK arc segment knob, B boat of the diamond knife Tissue Freezing, Testicular Biopsy Mini-bank, and Testicular Sperm Extraction Tissue in the sperm-freezing medium is subjected to programmed freezing using a freezing device (in our case, Nicool 100 [Air Liquide, Marne-laVallée, France]).
4 Early Development of the Human Testis Gordana Jurić-Lekić, Marta Himelreich, Marta Lekić, Ðurđica Grbeša, and Floriana Bulić-Jakuš The gonads (testes and ovaries) are derived from three sources: the mesothelium (mesodermal epithelium) lining the posterior abdominal wall, underlying mesenchyme (embryonic connective tissue), and primordial germ cells. The initial stages of gonadal development occur during the fifth week, when a thickened area of mesothelium develops on the medial side of the mesonephros.
2001;76(2): 380–3. Nagy ZP, Verheyen G, Tournaye H, Devroey P, Van Steirteghem AC. An improved treatment procedure for testicular biopsy specimens offers more efficient sperm recovery: case series. Fertil Steril. 1997;68(2):376–9. Nicopoullos JD, Gilling-Smith C, Almeida PA, NormanTaylor J, Grace I, Ramsay JW. Use of surgical sperm retrieval in azoospermic men: a meta-analysis. Fertil Steril. 2004;82(3):691–701. Ostad M, Liotta D, Ye Z, Schlegel PN. Testicular sperm extraction for nonobstructive azoospermia: results of a multibiopsy approach with optimized tissue dispersion.